In recent months one of the main development areas of CytoBuoy has been the optimization of the picturing equipment: Image in Flow. The source of illumination has been changed from a coherent (laser) light source to an incoherent (LED) light source. This new technique removes the fringes and rings found in slightly out-of-focus images made with the previous image in flow system. The defocus with an incoherent light source looks much more like a defocus encountered with our own eyes. This leads to more beautiful pictures, in which the internal structure and details of the cells are much more visible!