Fungi monitoring in filamentous bioprocess

The researchers from TU Wien monitored spore germination real-time by means of a CytoSense with accuracy >95%. Analysis of stained Penicillium chrysogenum spore with a CytoSense revealed activation of their metabolic activity and simultaneous change in their size and surface character. This flow cytometric analysis was possible despite the presence of other particles common for complex media used in filamentous bioprocess.